| Arizona Cardinals | Injury | Status | Expected Return |
| Owen Hantschel | Concussion | Out (in concussion protocol) | 2 Weeks |
| Blaine Simmons | Torn Thumb Ligament | Probable | 1 Week |
| Jamaal Hodges | Sprained Knee | Probable | 1 Week |
| Ross Riddock | Deep Thigh Bruise | Probable | 1 Week |
| Ethan Santagate | Pulled Calf Muscle | Questionable | 1 Week |
| K.C. Terrell | None | 100% |
|
| Atlanta Falcons | Injury | Status | Expected Return |
| Miles Desmond | Strained Quadriceps Muscle | Probable | 2 Weeks |
| Alec Borrelli | Knee Contusion | Probable | 1 Week |
| Terrence Kevorkian | Broken Nose | Probable | 1 Week |
| Baltimore Ravens | Injury | Status | Expected Return |
| Randal Cooley | Shoulder Tendinitis | Probable | 1 Week |
| Lamont Watson | Bruised Ribcage | Probable | 1 Week |
| Orlando Tylski | None | 100% |
|
| Alexander Ellard | None | 100% |
|
| Gilbert Sheasley | None | 100% |
|
| Buffalo Bills | Injury | Status | Expected Return |
| Wesley Clark | Turf Toe | Doubtful | Unknown |
| Leslie Eriksen | Concussion | Out (in concussion protocol) | 8 Weeks |
| Sammie Durham | High Ankle Sprain | Out | 8 Weeks |
| Dixon Lane | Sprained Lateral Knee Ligament | Probable | 3 Weeks |
| Cole Schrempf | Hyperextended Elbow | Out | 3 Weeks |
| Isaac Dunn | Hyperextended Knee | Doubtful | 2 Weeks |
| Gustavo Dzwonczyk | Bad Cold | Probable | 1 Week |
| Rob Anthony | Concussion | Out (in concussion protocol) | 1 Week |
| Rusty Worcester | Deep Thigh Bruise | Probable | 1 Week |
| J.J. Marsh | None | 100% |
|
| Caleb Bellando | None | 100% |
|
| Gino Jobe | None | 100% |
|
| Carolina Panthers | Injury | Status | Expected Return |
| Jacob Grudich | Ankle Surgery | Out | 16 Weeks |
| Rickey Shaw | Sprained Thumb | Probable | 4 Weeks |
| Ezekiel Lindsay | Sprained Knee | Questionable | 3 Weeks |
| Antoine Kesselman | Viral Infection | Questionable | 2 Weeks |
| Leonard Vajda | Pulled Groin | Questionable | 2 Weeks |
| Alonzo Cote | Tonsilitis | Out | 2 Weeks |
| Malik Perry | None | 100% |
|
| Chicago Bears | Injury | Status | Expected Return |
| Buddy Penberthy | Turf Toe | Doubtful | Unknown |
| Lenny Flynn | Compound Leg Fracture | Out | 48 Weeks |
| Ernie Lyle | Reconstructive Knee Surgery | Out | 48 Weeks |
| Duane Fenno | Sprained Lateral Knee Ligament | Questionable | 6 Weeks |
| Kevin Spruce | Shin Splints | Probable | 2 Weeks |
| Joey Caldwell | Elbow Contusion | Probable | 1 Week |
| David Shepherd | Bad Cold | Probable | 1 Week |
| Manuel Butler | None | 100% |
|
| Carter Duncan | None | 100% |
|
| Cincinnati Bengals | Injury | Status | Expected Return |
| Brock Wayne | Degenerative Hip Condition | Out | 85 Weeks |
| Joe Bennett | Torn Rotator Cuff | Out | 15 Weeks |
| Matt Kingry | Strained Back | Doubtful | 2 Weeks |
| Chase Arnold | Sprained Knee | Probable | 1 Week |
| Jamie Link | Hyperextended Knee | Probable | 1 Week |
| Braxton Chan | Sprained Ankle | Probable | 1 Week |
| Kyle Zardiackas | None | 100% |
|
| Leo Watson | None | 100% |
|
| Kurt Bush | None | 100% |
|
| Cleveland Browns | Injury | Status | Expected Return |
| Amari Turner | Concussion | Out (in concussion protocol) | 9 Weeks |
| Aidan Sims | Hyperextended Knee | Out | 3 Weeks |
| Wesley Lane | Hyperextended Knee | Doubtful | 2 Weeks |
| Cameron Fulcher | Hyperextended Elbow | Questionable | 2 Weeks |
| Ian Brian | Knee Bursitis | Probable | 1 Week |
| Deron Castaneda | Sprained Ankle | Probable | 1 Week |
| Benjamin Eickholt | Knee Tendinitis | Probable | 1 Week |
| Rex Hampton | Sprained Knee | Probable | 1 Week |
| David Kieffer | None | 100% |
|
| Dallas Cowboys | Injury | Status | Expected Return |
| Clayton Sweeney | Pulled Calf Muscle | Out | 6 Weeks |
| Darren Givens | Sprained Knee | Questionable | 4 Weeks |
| Blaine Hickman | Strained Achilles Tendon | Out | 3 Weeks |
| DeAndre Tanner | Shoulder Tendinitis | Probable | 1 Week |
| Mickey Jansen | None | 100% |
|
| Denver Broncos | Injury | Status | Expected Return |
| Earnest Rhodes | Torn Knee Cartilage | Out | 6 Weeks |
| Nicholas Petitgout | Broken Wrist | Out | 4 Weeks |
| Mo Enos | Strained Triceps Muscle | Probable | 2 Weeks |
| Ethan Ricks | Strained Elbow Tendon | Probable | 1 Week |
| Detroit Lions | Injury | Status | Expected Return |
| Christian Kemp | Bruised Sternum | Probable | 3 Weeks |
| Tyrone Hastings | Knee Tendinitis | Questionable | 3 Weeks |
| Sammy Buning | Strained Calf Muscle | Probable | 1 Week |
| Steven Gulbrandsen | Separated Shoulder | Probable | 1 Week |
| Green Bay Packers | Injury | Status | Expected Return |
| Kris Hamilton | Sprained Neck | Probable | 4 Weeks |
| Seth Manculich | Concussion | Out (in concussion protocol) | 4 Weeks |
| Les Carach | Broken Ankle | Probable | 1 Week |
| Wayne Buckner | Bruised Ribcage | Probable | 1 Week |
| Jason McSwain | None | 100% |
|
| Cole Loy | None | 100% |
|
| Raul Hodges | None | 100% |
|
| Houston Texans | Injury | Status | Expected Return |
| Aaron Blackwell | Concussion | Out (in concussion protocol) | 5 Weeks |
| Spencer Campbell | Hyperextended Elbow | Out | 3 Weeks |
| Irv Detsch | Strained Elbow Tendon | Probable | 1 Week |
| Indianapolis Colts | Injury | Status | Expected Return |
| Carter Clark | Severe Depression | Out | Unknown |
| Keegan Uhl | Sprained Knee | Questionable | 4 Weeks |
| Oscar Joyner | Sprained Lateral Knee Ligament | Probable | 3 Weeks |
| Travis Miller | Severe Wrist Sprain | Probable | 2 Weeks |
| Rodolfo Ogden | Viral Infection | Questionable | 1 Week |
| Leomont Matthews | None | 100% |
|
| Jacksonville Jaguars | Injury | Status | Expected Return |
| Allen Hand | Bruised Sternum | Questionable | 8 Weeks |
| Carl Broestl | Broken Thumb | Questionable | 3 Weeks |
| Liam Kennedy | Bruised Ribcage | Probable | 3 Weeks |
| Hector Amadro | Sprained Knee | Questionable | 2 Weeks |
| Frederick Skrepenak | Bruised Heel | Probable | 2 Weeks |
| Samuel Boettcher | Bruised Heel | Probable | 2 Weeks |
| Emmanuel Frederick | Sprained Knee | Questionable | 2 Weeks |
| Todd Shepherd | Sprained Thumb | Probable | 1 Week |
| Jerrian Stuart | Sprained Ankle | Questionable | 1 Week |
| Ted Nomellini | Severe Wrist Sprain | Probable | 1 Week |
| Damon Dibble | None | 100% |
|
| Miles Lynn | None | 100% |
|
| Joel Durden | None | 100% |
|
| Kansas City Chiefs | Injury | Status | Expected Return |
| Jonathan Hartman | Strained Hamstring | Questionable | Unknown |
| Wendell Shepherd | Severe Hamstring Pull | Out | 8 Weeks |
| Ian Bauer | Knee Tendinitis | Probable | 3 Weeks |
| Norm Robbins | Knee Bursitis | Probable | 2 Weeks |
| Danny Rose | Concussion | Out (in concussion protocol) | 2 Weeks |
| Silas Braham | None | 100% |
|
| Jay Wagner | None | 100% |
|
| Los Angeles Rams | Injury | Status | Expected Return |
| Gilbert Huntley | Broken Clavicle | Out | 7 Weeks |
| Devin Beane | Broken Clavicle | Out | 5 Weeks |
| Nicolas Idomir | Strained Rotator Cuff | Probable | 2 Weeks |
| Fernando Meier | Sprained Ankle | Probable | 2 Weeks |
| Gustavo Tiffee | None | 100% |
|
| Lionel Bensen | None | 100% |
|
| Miami Dolphins | Injury | Status | Expected Return |
| Malik Frederick | Strained Achilles Tendon | Out | 4 Weeks |
| Braxton Grant | Knee Tendinitis | Probable | 3 Weeks |
| Johnnie Manning | Sprained Knee | Questionable | 3 Weeks |
| Maurice Bell | Sprained Knee | Probable | 1 Week |
| Erick Curtis | Bad Cold | Probable | 1 Week |
| Scottie Humble | None | 100% |
|
| Sammie O'Neill | None | 100% |
|
| Minnesota Vikings | Injury | Status | Expected Return |
| Jeffery Cash | Turf Toe | Doubtful | Unknown |
| Glenn Fackleman | Bruised Sternum | Probable | 5 Weeks |
| James Buel | Sprained Knee | Questionable | 2 Weeks |
| Archie Huston | Strained Calf Muscle | Out | 2 Weeks |
| Darrin Butts | Concussion | Out (in concussion protocol) | 1 Week |
| Darrell Lekin | None | 100% |
|
| Troy Stephenson | None | 100% |
|
| New England Patriots | Injury | Status | Expected Return |
| Axel Melino | ACL Knee Surgery | Probable | 6 Weeks |
| Timothy Guthrie | Pulled Groin | Questionable | 2 Weeks |
| Logan Alexander | Knee Bursitis | Probable | 1 Week |
| New Jersey Jets | Injury | Status | Expected Return |
| Wes Keyser | High Ankle Sprain | Out | 12 Weeks |
| Albert Horn | Bruised Sternum | Probable | 7 Weeks |
| Ronald Williams | Broken Wrist | Doubtful | 5 Weeks |
| Ed Thornton | Concussion | Out (in concussion protocol) | 3 Weeks |
| Wes Leisure | Sprained Knee | Questionable | 2 Weeks |
| Jamal Ramsey | Broken Toe | Probable | 2 Weeks |
| Shawn Sims | Bruised Ribcage | Probable | 2 Weeks |
| Horace Hinsley | Concussion | Out (in concussion protocol) | 1 Week |
| Conrad Blakely | Broken Finger | Probable | 1 Week |
| Tony Johns | None | 100% |
|
| Parker Keith | None | 100% |
|
| Martin Freuler | None | 100% |
|
| New Orleans Saints | Injury | Status | Expected Return |
| Gene Godfrey | Concussion | Out (in concussion protocol) | 6 Weeks |
| Kim Maloney | Broken Tibia | Out | 5 Weeks |
| Abraham Archie | High Ankle Sprain | Probable | 2 Weeks |
| Conrad Ulufale | MCL Damage to the Knee | Doubtful | 1 Week |
| Hayden Harden | None | 100% |
|
| Brock Bernard | None | 100% |
|
| Damien Welker | None | 100% |
|
| Josh Perkins | None | 100% |
|
| New York Giants | Injury | Status | Expected Return |
| Lonnie Sporzynski | Concussion | Out (in concussion protocol) | 5 Weeks |
| Malcolm Parrish | Knee Tendinitis | Probable | 4 Weeks |
| Donnie Straight | Severe Hamstring Pull | Doubtful | 4 Weeks |
| Devonte Tank | Shoulder Tendinitis | Probable | 3 Weeks |
| Van Saavedra | Deep Thigh Bruise | Probable | 2 Weeks |
| Irving Cole | Broken Clavicle | Questionable | 2 Weeks |
| Preston Legay | Hyperextended Knee | Questionable | 2 Weeks |
| Tanner Whiting | Shoulder Tendinitis | Probable | 1 Week |
| Mason Alcott | Strained Rotator Cuff | Probable | 1 Week |
| Shaun Fabbrizzi | None | 100% |
|
| Mason Pelshak | None | 100% |
|
| Blake Andrews | None | 100% |
|
| Seth Barker | None | 100% |
|
| Oakland Raiders | Injury | Status | Expected Return |
| Dean Cochrane | Sprained Neck | Probable | 3 Weeks |
| Gilbert McElroy | Concussion | Out (in concussion protocol) | 3 Weeks |
| Lee Acker | Sprained Thumb | Probable | 2 Weeks |
| Levi Patterson | Torn Knee Cartilage | Questionable | 2 Weeks |
| Kris Howard | Strained Calf Muscle | Out | 2 Weeks |
| Cornell Stith | Bruised Ribcage | Probable | 1 Week |
| Craig Simmons | None | 100% |
|
| Ricardo Hempstead | None | 100% |
|
| Philadelphia Eagles | Injury | Status | Expected Return |
| Lenny Freysinger | Severe Anxiety | Out | Unknown |
| Van Williamson | Torn Lateral Knee Ligament | Out | 9 Weeks |
| Matthew Agin | Torn Knee Cartilage | Questionable | 3 Weeks |
| Wally Bono | Bruised Ribcage | Probable | 1 Week |
| Christian Cassidy | None | 100% |
|
| Pittsburgh Steelers | Injury | Status | Expected Return |
| Jeffery Shea | Concussion | Out (in concussion protocol) | 6 Weeks |
| Ralph Randall | Strained Patellar Tendon | Doubtful | 4 Weeks |
| Joey Robbins | Sprained Knee | Questionable | 3 Weeks |
| Lamont Hemphill | Broken Foot | Questionable | 2 Weeks |
| Carson Fulcher | Sprained Knee | Probable | 2 Weeks |
| Dashawn Nelson | None | 100% |
|
| San Diego Chargers | Injury | Status | Expected Return |
| Fred Roscoe | Strained Hamstring | Questionable | Unknown |
| Vernon Kimbrough | Compound Leg Fracture | Out | 34 Weeks |
| Alec Beyt | ACL Damage to the Knee | Out | 14 Weeks |
| Fred Coles | Knee Tendinitis | Probable | 4 Weeks |
| Howie Ramirez | Broken Toe | Probable | 2 Weeks |
| Tevin Sampson | Bruised Ribcage | Probable | 1 Week |
| Ben Clayton | None | 100% |
|
| San Francisco 49ers | Injury | Status | Expected Return |
| Everett Reese | Knee Tendinitis | Probable | 3 Weeks |
| Glenn Delgado | Shin Splints | Questionable | 3 Weeks |
| Raul Gonzalez | Strained Foot Ligament | Out | 2 Weeks |
| Bennett Strickland | Broken Arm | Questionable | 2 Weeks |
| Wendell Malone | Hyperextended Knee | Doubtful | 2 Weeks |
| Devonte Woods | Separated Shoulder | Probable | 1 Week |
| Sam Giles | None | 100% |
|
| Eric Powell | None | 100% |
|
| Leon Howard | None | 100% |
|
| Seattle Seahawks | Injury | Status | Expected Return |
| Rickey Solley | Broken Foot | Out | 9 Weeks |
| Juan Reilly | Shoulder Tendinitis | Probable | 2 Weeks |
| Amos Shaye | None | 100% |
|
| B.J. Bullock | None | 100% |
|
| Tampa Bay Buccaneers | Injury | Status | Expected Return |
| Jordan England | Strained Hamstring | Questionable | Unknown |
| Zach McSherry | Broken Ribs | Out | 6 Weeks |
| Noah Summers | Broken Ankle | Out | 5 Weeks |
| Tyrone Kemp | Dislocated Elbow | Out | 5 Weeks |
| Daniel Weber | Hyperextended Knee | Out | 3 Weeks |
| Cedric Griffiths | Shoulder Tendinitis | Probable | 2 Weeks |
| Chad McConnell | Influenza | Probable | 1 Week |
| Donald Cash | Influenza | Probable | 1 Week |
| Trent Meeker | Influenza | Probable | 1 Week |
| Hugh Salley | Influenza | Probable | 1 Week |
| Shaquille Dixon | Influenza | Probable | 1 Week |
| Luke Woodard | Influenza | Probable | 1 Week |
| Alexis Piccarreta | Influenza | Probable | 1 Week |
| Archie Kolodzik | None | 100% |
|
| Pedro Chisholm | None | 100% |
|
| Ivan Wright | None | 100% |
|
| Jorge Samuels | None | 100% |
|
| Harry Perez | None | 100% |
|
| Reuben Iverson | None | 100% |
|
| Norm Stonge | None | 100% |
|
| Logan Armstrong | None | 100% |
|
| Grant Sweeney | None | 100% |
|
| Tennessee Titans | Injury | Status | Expected Return |
| Wayne Lunderville | Repetitive Concussion Syndrome | Out | 83 Weeks |
| Robert Davidson | Broken Foot | Out | 6 Weeks |
| Donnie Lucas | Severe Wrist Sprain | Out | 5 Weeks |
| Kelly Spencer | Strained Achilles Tendon | Out | 2 Weeks |
| Morris McWilliams | Strained Patellar Tendon | Doubtful | 2 Weeks |
| Norbert Sylvester | None | 100% |
|
| Harold Richardson | None | 100% |
|
| Washington Commanders | Injury | Status | Expected Return |
| Dexter Burks | Broken Tibia | Out | 6 Weeks |
| Donald Delgado | Broken Thumb | Questionable | 5 Weeks |
| Tyrell Middleton | Concussion | Out (in concussion protocol) | 1 Week |
| Dan Warren | Hyperextended Elbow | Probable | 1 Week |