| Arizona Cardinals | Injury | Status | Expected Return |
| Jesse Hamaoka | High Ankle Sprain | Questionable | 6 Weeks |
| Josh Barton | Bruised Ribcage | Probable | 2 Weeks |
| Harris Newton | Hyperextended Knee | Probable | 1 Week |
| Atlanta Falcons | Injury | Status | Expected Return |
| Bo Dent | Strained Adductor Muscle | Out | 3 Weeks |
| Marcus Cooley | Concussion | Out (in concussion protocol) | 2 Weeks |
| Bo Glenn | Broken Clavicle | Questionable | 2 Weeks |
| Baltimore Ravens | Injury | Status | Expected Return |
| Jaylen Mayes | Strained Hamstring | Questionable | Unknown |
| Shaun Ellis | Concussion | Out (in concussion protocol) | 6 Weeks |
| Deron MacDowell | Broken Clavicle | Doubtful | 3 Weeks |
| Russell Picchietti | Shin Splints | Probable | 2 Weeks |
| Roderick Tomich | Strained Rotator Cuff | Probable | 2 Weeks |
| Vernon Becker | Sprained Neck | Probable | 2 Weeks |
| Brody Hickman | Abdominal Strain | Probable | 1 Week |
| Harold Gray | Bruised Ribcage | Probable | 1 Week |
| K.C. Long | None | 100% |
|
| Nicolas Idomir | None | 100% |
|
| Buffalo Bills | Injury | Status | Expected Return |
| Devin Liles | Turf Toe | Doubtful | Unknown |
| Ronald Williams | Strained Hamstring | Questionable | Unknown |
| David Erickson | Torn Biceps Muscle | Out | 17 Weeks |
| Chris Forbes | Shoulder Surgery | Out | 14 Weeks |
| Roosevelt Alcott | Dislocated Shoulder | Out | 2 Weeks |
| Allen Flowers | Strained Achilles Tendon | Probable | 1 Week |
| Dalton Wilkes | Hyperextended Elbow | Probable | 1 Week |
| Nick Hartwig | None | 100% |
|
| Carolina Panthers | Injury | Status | Expected Return |
| Jonah Hruby | Turf Toe | Doubtful | Unknown |
| Toby Arnold | Reconstructive Knee Surgery | Out | 34 Weeks |
| Johnny Steen | Elbow Ligament Surgery | Out | 20 Weeks |
| Moe Siglar | ACL Damage to the Knee | Out | 8 Weeks |
| Leonard Rutan | Pulled Calf Muscle | Out | 3 Weeks |
| Donnell Maddux | Herniated Disk | Probable | 1 Week |
| Johnnie Lampkin | Knee Bursitis | Probable | 1 Week |
| Ashton Richmond | Severe Hamstring Pull | Probable | 1 Week |
| William Barginski | None | 100% |
|
| Kai Henderson | None | 100% |
|
| Chicago Bears | Injury | Status | Expected Return |
| Brandon Swift | Reconstructive Knee Surgery | Out | 26 Weeks |
| Carter Duncan | Concussion | Out (in concussion protocol) | 3 Weeks |
| Isaiah Rose | Deep Thigh Bruise | Probable | 2 Weeks |
| Joey Caldwell | Sprained Knee | Questionable | 2 Weeks |
| Martin Van Pelt | Torn Thumb Ligament | Probable | 1 Week |
| Albert Meadows | Elbow Bursitis | Probable | 1 Week |
| Stephen Irwin | None | 100% |
|
| Lenny Hooper | None | 100% |
|
| Cincinnati Bengals | Injury | Status | Expected Return |
| Kyle Zardiackas | Strained Hamstring | Questionable | Unknown |
| Wes Berkhofer | Severe Hamstring Pull | Out | 10 Weeks |
| Fernando Meadows | Concussion | Out (in concussion protocol) | 2 Weeks |
| Jamie Link | Knee Tendinitis | Probable | 2 Weeks |
| Andre Kiel | Broken Toe | Probable | 1 Week |
| Howie Baumann | Hyperextended Elbow | Probable | 1 Week |
| Greg McFall | Broken Finger | Probable | 1 Week |
| Claude Gavalas | None | 100% |
|
| Leon Thurman | None | 100% |
|
| Horace Cox | None | 100% |
|
| Cleveland Browns | Injury | Status | Expected Return |
| Cameron Fulcher | Strained Hamstring | Questionable | Unknown |
| Benjamin Eickholt | ACL Knee Surgery | Out | 48 Weeks |
| Bennett Middleton | Strained Rotator Cuff | Probable | 3 Weeks |
| Blake Malone | Shin Splints | Probable | 3 Weeks |
| Giovanni Sinclair | None | 100% |
|
| Marc Lane | None | 100% |
|
| Dallas Cowboys | Injury | Status | Expected Return |
| Jay Ozols | Strained Hamstring | Questionable | Unknown |
| Vernon Carlson | Strained Hamstring | Questionable | Unknown |
| Philip Jacobs | ACL Knee Surgery | Out | 46 Weeks |
| Erick Humes | ACL Knee Surgery | Out | 39 Weeks |
| Abel Jarvis | Strained Elbow Tendon | Probable | 2 Weeks |
| Harry Dennis | None | 100% |
|
| Denver Broncos | Injury | Status | Expected Return |
| Terrance Jasso | Torn Lateral Knee Ligament | Out | 11 Weeks |
| Nate Granados | Severe Hamstring Pull | Probable | 3 Weeks |
| Camden Hanson | Hyperextended Knee | Questionable | 2 Weeks |
| Kyle Stott | Pulled Calf Muscle | Questionable | 1 Week |
| Robbie Lang | None | 100% |
|
| Kelly Springs | None | 100% |
|
| Detroit Lions | Injury | Status | Expected Return |
| Shannon Ottis | ACL Damage to the Knee | Questionable | 3 Weeks |
| Bert Hanshew | Shoulder Tendinitis | Probable | 1 Week |
| Herman Talley | None | 100% |
|
| Green Bay Packers | Injury | Status | Expected Return |
| Russell Jordan | MCL Knee Surgery | Out | 13 Weeks |
| Josiah Meggett | Broken Clavicle | Out | 4 Weeks |
| Dylan Delhomme | Sprained Thumb | Probable | 1 Week |
| Phillip Sheldon | None | 100% |
|
| Houston Texans | Injury | Status | Expected Return |
| Eddie Berner | Concussion | Out (in concussion protocol) | 4 Weeks |
| Alfredo Barton | Broken Tibia | Out | 3 Weeks |
| Aaron Blackwell | Severe Wrist Sprain | Probable | 1 Week |
| Indianapolis Colts | Injury | Status | Expected Return |
| J.R. Binkow | Ruptured Elbow Tendon | Out | 39 Weeks |
| Taylor Newhouse | High Ankle Sprain | Questionable | 3 Weeks |
| Alex Hamilton | Strained Elbow Tendon | Probable | 2 Weeks |
| Kody Freeman | None | 100% |
|
| Craig Simmons | None | 100% |
|
| Jacksonville Jaguars | Injury | Status | Expected Return |
| Emmanuel Frederick | High Ankle Sprain | Doubtful | 9 Weeks |
| Geoff Fox | Severe Hamstring Pull | Out | 6 Weeks |
| Arturo Joseph | Concussion | Out (in concussion protocol) | 1 Week |
| Jared Neitring | Separated Shoulder | Probable | 1 Week |
| Mickey Cooper | Sprained Knee | Probable | 1 Week |
| Kai Martinez | Strained Quadriceps Muscle | Probable | 1 Week |
| Carl Broestl | Strained Triceps Muscle | Probable | 1 Week |
| Billy Austin | Separated Shoulder | Probable | 1 Week |
| Miles Lynn | None | 100% |
|
| Jerrian Stuart | None | 100% |
|
| Kansas City Chiefs | Injury | Status | Expected Return |
| Gregory Eppright | Strained Hamstring | Questionable | Unknown |
| Josiah Bush | ACL Knee Surgery | Out | 22 Weeks |
| Kent Landis | Torn Lateral Knee Ligament | Out | 15 Weeks |
| Francisco Alvarado | Severe Hamstring Pull | Out | 13 Weeks |
| Brody Hirshberg | Sprained Lateral Knee Ligament | Probable | 6 Weeks |
| Kelvin Rodgers | Pulled Groin | Doubtful | 4 Weeks |
| Wyatt Duckett | Dislocated Elbow | Questionable | 1 Week |
| Carlos Nalen | Hyperextended Knee | Probable | 1 Week |
| Gage Hanks | None | 100% |
|
| Derek Gaiter | None | 100% |
|
| Los Angeles Rams | Injury | Status | Expected Return |
| Warren Dulles | Pulled Calf Muscle | Questionable | 2 Weeks |
| Austin Angel | Bruised Sternum | Probable | 2 Weeks |
| Quentin Gilchrist | Strained Elbow Tendon | Probable | 1 Week |
| Sam Wayne | Strained Achilles Tendon | Probable | 1 Week |
| Miami Dolphins | Injury | Status | Expected Return |
| Winfred Herbert | Turf Toe | Doubtful | Unknown |
| J.R. Talley | Torn Ankle Ligament | Out | 14 Weeks |
| Kaden West | Concussion | Out (in concussion protocol) | 8 Weeks |
| Devon Gallardo | Concussion | Out (in concussion protocol) | 4 Weeks |
| Leon Bandhauer | Sprained Knee | Probable | 2 Weeks |
| Butch Bethea | Strained Calf Muscle | Probable | 2 Weeks |
| Clifton Rasmussen | Bruised Ribcage | Probable | 1 Week |
| Richard Sanchez | None | 100% |
|
| Minnesota Vikings | Injury | Status | Expected Return |
| Ty Martinez | Strained Quadriceps Muscle | Probable | 2 Weeks |
| Phil Sell | None | 100% |
|
| Ronnie Doss | None | 100% |
|
| New England Patriots | Injury | Status | Expected Return |
| Micah Mang | Torn Quadriceps Muscle | Out | 39 Weeks |
| Ellis Roberts | Ruptured Adductor Muscle | Out | 14 Weeks |
| Dan O'Donnell | ACL Damage to the Knee | Out | 9 Weeks |
| Dexter Alexander | Torn Rotator Cuff | Questionable | 4 Weeks |
| Gerald Nkwenti | Sprained Ankle | Probable | 2 Weeks |
| Brett Austin | Sprained Ankle | Probable | 2 Weeks |
| Kai Burroughs | Back Surgery | Probable | 1 Week |
| Trevor Newman | None | 100% |
|
| New Jersey Jets | Injury | Status | Expected Return |
| No Injured Players |
| New Orleans Saints | Injury | Status | Expected Return |
| Richard Dixon | Strained Hamstring | Questionable | Unknown |
| William Kemp | Stress Fracture in the Leg | Out | 6 Weeks |
| J.J. Gregoire | Knee Tendinitis | Probable | 2 Weeks |
| Richie Bradshaw | Knee Bursitis | Probable | 1 Week |
| Lionel Burkhammer | None | 100% |
|
| New York Giants | Injury | Status | Expected Return |
| Trenton Orton | Strained Hamstring | Questionable | Unknown |
| Braxton Jacobs | Broken Tibia | Questionable | 2 Weeks |
| K.C. Renteria | None | 100% |
|
| Shaun Fabbrizzi | None | 100% |
|
| Ezra Fisher | None | 100% |
|
| Xavier Winger | None | 100% |
|
| Oakland Raiders | Injury | Status | Expected Return |
| Rickey Chatham | Strained Hamstring | Questionable | Unknown |
| Chance Glover | Turf Toe | Doubtful | Unknown |
| Drake Kudlacz | Repetitive Concussion Syndrome | Out | 83 Weeks |
| Vinny Merriday | Reconstructive Knee Surgery | Out | 29 Weeks |
| Levi Patterson | Knee Tendinitis | Probable | 2 Weeks |
| Henry Hockman | Sprained Knee | Probable | 2 Weeks |
| Geoff Boeck | None | 100% |
|
| Philadelphia Eagles | Injury | Status | Expected Return |
| Leon Henley | Strained Hamstring | Questionable | Unknown |
| Chase Borrego | Concussion | Out (in concussion protocol) | 2 Weeks |
| Reginald Eide | Knee Tendinitis | Probable | 2 Weeks |
| Christian Cassidy | Strained Rotator Cuff | Probable | 1 Week |
| Cristian Henry | Strained Achilles Tendon | Probable | 1 Week |
| Pittsburgh Steelers | Injury | Status | Expected Return |
| Lamont Hemphill | High Ankle Sprain | Out | 14 Weeks |
| Bobby Kelley | Torn Knee Cartilage | Out | 5 Weeks |
| Jeffery Shea | Strained Achilles Tendon | Out | 3 Weeks |
| Dashawn Nelson | Separated Shoulder | Probable | 2 Weeks |
| Hector Clements | Broken Toe | Probable | 1 Week |
| Harold Bryson | Shoulder Tendinitis | Probable | 1 Week |
| Marty Camarillo | None | 100% |
|
| Johnnie Manning | None | 100% |
|
| Joey Robbins | None | 100% |
|
| Parker Keith | None | 100% |
|
| San Diego Chargers | Injury | Status | Expected Return |
| Jermaine Bush | Ruptured Elbow Tendon | Out | 31 Weeks |
| Asher Perez | Compound Leg Fracture | Out | 23 Weeks |
| Derek Chafee | Strained Quadriceps Muscle | Probable | 1 Week |
| Alejandro Crawford | Strained Patellar Tendon | Probable | 1 Week |
| Corbin Palmer | None | 100% |
|
| Roberto Gamble | None | 100% |
|
| San Francisco 49ers | Injury | Status | Expected Return |
| Alfred Jenkins | Degenerative Hip Condition | Out | 68 Weeks |
| Lance Whitt | Separated Shoulder | Questionable | 3 Weeks |
| Billy Gill | ACL Knee Surgery | Probable | 1 Week |
| Herb Owens | None | 100% |
|
| Quentin Kean | None | 100% |
|
| Avery Schindler | None | 100% |
|
| Seattle Seahawks | Injury | Status | Expected Return |
| Neil Durham | Turf Toe | Doubtful | Unknown |
| Marco Manning | Torn Lateral Knee Ligament | Questionable | 3 Weeks |
| Rickey Shaw | Strained Quadriceps Muscle | Probable | 1 Week |
| B.J. Brookes | None | 100% |
|
| Irving Harmon | None | 100% |
|
| Bruce Akroyd | None | 100% |
|
| Tampa Bay Buccaneers | Injury | Status | Expected Return |
| Micah Paige | ACL Damage to the Knee | Out | 14 Weeks |
| Joel Wolfe | Broken Hand | Probable | 2 Weeks |
| Hugh Salley | Concussion | Out (in concussion protocol) | 2 Weeks |
| Charles Cunningham | Sprained Knee | Probable | 1 Week |
| Tennessee Titans | Injury | Status | Expected Return |
| Larry Chapman | High Ankle Sprain | Out | 13 Weeks |
| Morris McWilliams | Strained Back | Out | 3 Weeks |
| Dominique Stephenson | Hyperextended Elbow | Questionable | 2 Weeks |
| Edward Blades | Shoulder Tendinitis | Probable | 1 Week |
| Edwin Badgro | Sprained Knee | Probable | 1 Week |
| Jerald Harada | None | 100% |
|
| Irv McDonald | None | 100% |
|
| Chuck Copeland | None | 100% |
|
| Ramon Ripken | None | 100% |
|
| Washington Commanders | Injury | Status | Expected Return |
| Gene Mesaros | Strained Hamstring | Questionable | Unknown |
| Jumbo Berry | Strained Calf Muscle | Probable | 1 Week |
| Dwayne Peterson | None | 100% |
|